Blog Archives

Lecturer/Senior Lecturer in Genomics and Bioinformatics at Sheffield Hallam

Our neighbours at Sheffield Hallam University are currently advertising for a Lecturer/Senior Lecturer in Genomics and Bioinformatics. For full details and to apply, see the advert on jobs.ac.uk.… Full post
Posted in Expired vacancies

High-throughput identification of novel antimicrobial targets in Clostridium difficile

PhD available in Roy Chaudhuri‘s group, in collaboration with Rob Fagan. Clostridium difficile is an important human pathogen and the primary cause of antibiotic-associated infections in UK hospitals. The bacteria that reside in the human gut (the microbiota) normally prevent colonisation with C. difficile. However, treatment with antibiotics causes severe disruption to this community allowing C. difficile to establish an infection. C. difficile itself is highly resistant to most commonly used antibiotics and our treatment options are limited. There is an urgent need for the development of new antibiotics, particularly species-specific antimicrobials that can kill C. difficile without causing further damage to the microbiota.… Full post
Posted in Expired vacancies

Computational analysis of enhancer dysregulation in cancer

PhD position available in Ian Sudbery‘s group Dept/School/Faculty: Department of Molecular Biology and Biotechnology PhD Supervisor: Dr I Sudbery Application Deadline: Friday, January 30, 2015 How do cells integrate information to make decisions about what genes should be expressed at a given time and in a given place? How do these processes malfunction to produce disease states? The correct regulation of gene expression is essential for the proper functioning of the cell, and incorrect regulation of genes is central to the mechanisms of many diseases, not least cancer. Transcription of metazoan genes is regulated by sequences known as enhancers which integrate diverse signals to make decisions about expression, and then communicate these decisions through their interactions with promoters.… Full post
Posted in Expired vacancies

Developing novel OMICs tools to identify the origin of ancient bio samples using ancient DNA

PhD position available in Eran Elhaik‘s group: What percentage of our DNA came from the Vikings or Ancient Romans? How migration waves affected the environment? These and other questions can now be approached using ancient DNA and novel bioinformatics tools. Coupling Ancient DNA, which is one of the most exciting emerging fields in genetics, with tools, such as the Geographical Population Structure (GPS), which that can find one’s village of origin using our DNA (http://www.iflscience.com/health-and-medicine/dna-gps-maps-where-your-ancestors-lived), we can make historical and evolutionary inferences. The successful candidate will do some of the work in the ancient DNA lab in the University of York and in one of the world leading companies in DNA tests, located in Ohio (USA).… Full post
Posted in Expired vacancies

EPSRC Doctoral Training Grant Studentship

Application of machine learning to drive preclinical cancer drug discovery Supervisors: Dr James Bradford (Department of Oncology) and Professor Neil Lawrence (Department of Computer Science) A PhD student is sought with a strong computational background and a keen interest in applying their skills to cancer research Background Pre-clinical cancer models such as cell lines or xenografts are critical to the development of anti-cancer therapeutics and advancing our understanding of cancer biology. They are consistently used as a platform to investigate therapeutic mechanism of action and identify potential biomarkers prior to clinical trials in which similar exploration is often complicated, unethical and expensive.… Full post
Posted in Expired vacancies