Blog Archives

Lecturer/Senior Lecturer in Genomics and Bioinformatics at Sheffield Hallam

Our neighbours at Sheffield Hallam University are currently advertising for a Lecturer/Senior Lecturer in Genomics and Bioinformatics. For full details and to apply, see the advert on… Full post
Posted in Expired vacancies

NGS 2015 Sheffield: Human Disease Genomics

The third annual NGS 2015 Sheffield Conference takes place at Halifax Hall on 18th & 19th November 2015, run by Biotexcel in partnership with the Sheffield Children’s NHS Foundation Trust and The University of Sheffield. The theme of this year’s meeting is Human Disease Genomics. Further details are available at the conference website.… Full post
Posted in Past events

Largest human population sequencing study to date (UK10K project) published in Nature

The findings of the UK10K study, a project to sequence the genomes of nearly 10,000 individuals, mostly from the UK, have been published online in Nature. Lucy Crooks is one of the lead authors. The project performed whole genome sequencing on nearly 4,000 healthy individuals and exome sequencing of over 5,000 people affected with diseases including schizophrenia, obesity and a collection of rare diseases. The study explored the role of low frequency and rare variants in disease risk and provides a reference panel of genetic variation in the UK population to apply in future research.… Full post
Posted in News

Inaugural lecture by Professor Winston Hide: “Breaking the Human Genome Code – Opening Pandora’s Box?”

Professor Win Hide from the Bioinformatics Hub will be giving his inaugural lecture on Tuesday March 17th in the Medical School Lecture Theatre 2 at 5:15. Full details and booking form. Title: Breaking the Human Genome Code – Opening Pandora’s Box? Abstract: Recent technology advances have resulted in the ability to sequence anyone’s genome cheaply and quickly, but we are only just beginning the journey to discover the true meaning of our individual genomes. If you have your own genome sequenced, who should see it? How can we safely share a genome without ending up opening a whole new form of cybersnooping?… Full post
Posted in Past events

HPC@Sheffield Research Computing Event

The 2015 HPC@Sheffield research computing event will be held in Firth Hall on March 26th from 9.30-4.30. This year’s theme is “Global Grand Challenges”, and speakers include Oliver Hoffmann on “Community developed frameworks for large scale genome analysis”. Full details and registration.… Full post
Posted in Past events

High-throughput identification of novel antimicrobial targets in Clostridium difficile

PhD available in Roy Chaudhuri‘s group, in collaboration with Rob Fagan. Clostridium difficile is an important human pathogen and the primary cause of antibiotic-associated infections in UK hospitals. The bacteria that reside in the human gut (the microbiota) normally prevent colonisation with C. difficile. However, treatment with antibiotics causes severe disruption to this community allowing C. difficile to establish an infection. C. difficile itself is highly resistant to most commonly used antibiotics and our treatment options are limited. There is an urgent need for the development of new antibiotics, particularly species-specific antimicrobials that can kill C. difficile without causing further damage to the microbiota.… Full post
Posted in Expired vacancies

Computational analysis of enhancer dysregulation in cancer

PhD position available in Ian Sudbery‘s group Dept/School/Faculty: Department of Molecular Biology and Biotechnology PhD Supervisor: Dr I Sudbery Application Deadline: Friday, January 30, 2015 How do cells integrate information to make decisions about what genes should be expressed at a given time and in a given place? How do these processes malfunction to produce disease states? The correct regulation of gene expression is essential for the proper functioning of the cell, and incorrect regulation of genes is central to the mechanisms of many diseases, not least cancer. Transcription of metazoan genes is regulated by sequences known as enhancers which integrate diverse signals to make decisions about expression, and then communicate these decisions through their interactions with promoters.… Full post
Posted in Expired vacancies

Developing novel OMICs tools to identify the origin of ancient bio samples using ancient DNA

PhD position available in Eran Elhaik‘s group: What percentage of our DNA came from the Vikings or Ancient Romans? How migration waves affected the environment? These and other questions can now be approached using ancient DNA and novel bioinformatics tools. Coupling Ancient DNA, which is one of the most exciting emerging fields in genetics, with tools, such as the Geographical Population Structure (GPS), which that can find one’s village of origin using our DNA (, we can make historical and evolutionary inferences. The successful candidate will do some of the work in the ancient DNA lab in the University of York and in one of the world leading companies in DNA tests, located in Ohio (USA).… Full post
Posted in Expired vacancies

Past events

A list of previous Bioinformatics Hub events is available.… Full post
Posted in Events

Previous vacancies

A list of previous Bioinformatics Hub vacancies is provided for reference. Applications for these vacancies are no longer being accepted.… Full post
Posted in Vacancies